Steroids and derivatives
Medchemexpress LLC Cortisone 21-acetate (Standard) | 50-04-4 | 99.4% | 402.48 | 100 MG
Cortisone acetate (Standard) is the analytical standard of Cortisone acetate, intended for research and analytical applications. It is an oxidized metabolite of Cortisol (a Glucocorticoid) and functions as an immunosuppressant and anti-inflammatory agent. At high concentrations, Cortisone acetate can partially interfere with the binding of Glucocorticoid to the Glucocorticoid-receptor.
- Grade of analytical standard, supplied as a reference standard assay.
- Commonly used in qualitative, quantitative, and methodological research experiments.
- Suitable for use in HPLC, GC, and MS.
- Acts as an immunosuppressant.
- Acts as an anti-inflammatory agent.
- Purity of 99.39%.
Medchemexpress LLC Hydrocortisone acepo 50mg | 74050-20-7 | 460.56 g/mol | C26H36O7 | 50 MG
Hydrocortisone aceponate (hydrocortisone 17-propionate 21-acetate) is a topical glucocorticoid supplied as a research/analytical standard for laboratory use. It is provided as a solid reference material (CAS 74050-20-7) for in vitro and analytical studies and is not intended for therapeutic use.
- Topical glucocorticoid for dermatoses research.
- Provided as a research/analytical standard for laboratory applications.
- CAS number 74050-20-7 and chemical formula C26H36O7.
- Molecular weight ~460.56 g/mol.
- Purity reported by vendors; consult the certificate of analysis before use.
- Available in multiple pack sizes, including 50 mg.
Apexbio Technology LLC Dexamethasone phosphate disodium 2392-39-4 500mg
Dexamethasone phosphate disodium (CAS 2392-39-4) is a small-molecule agonist targeting the glucocorticoid receptor It is designed to modulate glucocorticoid-mediated signaling pathways thereby regulating immune and inflammatory responses Dexamethasone phosphate disodium exerts its biological activity primarily by binding to the glucocorticoid receptor initiating nuclear translocation and influencing gene transcription to suppress the expression and secretion of pro-inflammatory cytokines and chemokines Based on these pharmacological properties dexamethasone phosphate disodium holds research potential in studying inflammatory conditions immune response processes and associated signaling cascades in vitro and in vivo
TARGETMOL CHEMICALS INC 16alpha-Bromoepiandrosterone
Also available in 5 mg, 10 mg, 25 mg and bulk. Please contact Fisher for quotes. 16alpha-Bromoepiandrosterone (BEA) is a water-soluble synthetic sterol related to DHEA and is used in studies of type II diabetes and non-diabetic tuberculosis infections. Purity 98.99%
Medchemexpress LLC Dexamethasone palmitate | 14899-36-6 | 99.7% | 50 MG
Dexamethasone palmitate (DXP) is a prodrug of Dexamethasone, primarily utilized in inflammation research. It has demonstrated in vitro anti-inflammatory effects by decreasing LPS-induced MCP-1 and TNF-α concentrations in RAW 264.7 cells. In vivo studies in New Zealand White rabbits have shown that Dexamethasone palmitate, administered via IVT injection, distributes significantly in the vitreous humor and can control VEGF-induced vascular hyperpermeability.
- Appearance: Solid, white to off-white
- Purity: 99.68%
- Molecular weight: 630.87
- Formula: C38H59FO6
- Primarily for inflammation research
- Demonstrates in vitro anti-inflammatory effects (decreases LPS-induced MCP-1 and TNF-α)
- In vivo studies show significant distribution in vitreous humor and control of VEGF-induced vascular hyperpermeability
Medchemexpress LLC Hydrocortisone sodium phosphate | 6000-74-4 | MFCD00152562 | 99.1% | 486.40 g·mol⁻¹ | C21H29Na2O8P | 100 MG
Hydrocortisone sodium phosphate is the sodium phosphate ester of hydrocortisone, a short-acting glucocorticoid corticosteroid supplied as a white to off-white solid. Its water-soluble form is suitable for biochemical, pharmacological, and formulation studies where a soluble corticosteroid derivative is required.
- High purity: 99.1%.
- Water soluble for easy formulation and in vitro use.
- Molecular weight 486.40 g·mol⁻¹.
- White to off-white solid appearance.
- Provided in small pack sizes suitable for laboratory research.
Medchemexpress LLC Hydrocortisone acepo 25mg | 74050-20-7 | 460.56 g/mol | C26H36O7 | 25 MG
Hydrocortisone aceponate is supplied as an analytical standard for laboratory research into topical glucocorticoid activity. It is provided as a small solid pack appropriate for in vitro and analytical assays, with reported high purity and defined molecular properties.
- Purity listed as 97% for reliable analytical use.
- Molecular formula C26H36O7 and molecular weight 460.56 g/mol for accurate calculations.
- CAS number 74050-20-7 for unambiguous compound identification.
- Available in small pack sizes suitable for method development and standards preparation.
- Intended application: analytical and research use for dermal glucocorticoid studies.
Medchemexpress LLC Hydrocortisone cypionate | 508-99-6 | MFCD00083363 | 486.64 | 20 MG
Hydrocortisone cypionate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester, intended for research use only. It demonstrates diverse biological activities in vitro.
- Shows dose-dependent down-regulation of GR transcript in hCMEC/D3 cells and significantly increases TER across the hCMEC/D3 monolayer.
- Decreases expression of MHC II molecules, costimulatory molecule CD86, and DC-specific marker CD83 in treated dendritic cells, along with strongly reduced IL-12 secretion.
- Inhibits IFN-γ production but induces increased IL-4 release in dendritic cells.
- Reduces postischemic oxidative stress, perfusion pressure, transudate formation.
- Inhibits postischemic shedding of syndecan-1, heparan sulfate, and hyaluronan, as well as histamine release from mast cells.